Practical considerations regarding the use of genotype and pedigree data to model relatedness in the context of genome-wide association studies
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Cheng, Riyan; Parker , Clarissa C; Abney, Mark; Palmer, Abraham A
Description
Genome-wide association studies of complex traits often are complicated by relatedness among individuals. Ignoring or inappropriately accounting for relatedness often results in inflated type I error rates. Either genotype or pedigree data can be used to
Collections | ANU Research Publications |
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Date published: | 2013 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/77812 |
Source: | G3: Genes, Genomes, Genetics |
DOI: | 10.1534/g3.113.007948 |
Access Rights: | Open Access |
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01_Cheng_Practical_considerations_2013.pdf | 1.11 MB | Adobe PDF |
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