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Practical considerations regarding the use of genotype and pedigree data to model relatedness in the context of genome-wide association studies

Cheng, Riyan; Parker , Clarissa C; Abney, Mark; Palmer, Abraham A


Genome-wide association studies of complex traits often are complicated by relatedness among individuals. Ignoring or inappropriately accounting for relatedness often results in inflated type I error rates. Either genotype or pedigree data can be used to

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
Source: G3: Genes, Genomes, Genetics
DOI: 10.1534/g3.113.007948
Access Rights: Open Access


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