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Long-lasting spinal oxytocin analgesia is ensured by the stimulation of allopregnanolone synthesis which potentiates GABAA receptor-mediated synaptic inhibition

Breton, Jean-Didier; Juif, Pierre-Eric; Rajalu, Mathieu; Charlet, Alexandre; Goumon, Yannick; Poisbeau, Pierrick


Hypothalamospinal control of spinal pain processing by oxytocin (OT) has received a lot of attention in recent years because of its potency to reduce pain symptoms in inflammatory and neuropathic conditions. However, cellular and molecular mechanisms unde

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
Source: Journal of Neuroscience
DOI: 10.1523/JNEUROSCI.3084-12.2013


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