The multidrug resistance gene mdrla influences resistance to ectromelia virus infection by mechanisms other than conventional immunity
P-glycoprotein (P-gp), an ATP-dependent membrane pump encoded by mdr, plays, in addition to its ability to efflux toxins, a role in the resistance to pathogens. We employed mdr 1a gene knock out (mdr 1a-/-) mice and ectromelia virus (EV) to elucidate the
|Collections||ANU Research Publications|
|Source:||Immunology and Cell Biology|
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