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Dietary modification dampens liver inflammation and fibrosis in obesity-related fatty liver disease

Larter, Claire; Yeh, Matthew; Haigh, W Geoffrey; Van Rooyen, Derrick; Brooling, John; Heydet, Deborah; Nolan, Christopher; Teoh, Narcissus; Farrell, Geoffrey

Description

Background: Alms1 mutant (foz/foz) mice develop hyperphagic obesity, diabetes, metabolic syndrome, and fatty liver (steatosis). High-fat (HF) feeding converts pathology from bland steatosis to nonalcoholic steatohepatitis (NASH) with fibrosis, which leads

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
URI: http://hdl.handle.net/1885/77691
Source: Obesity
DOI: 10.1002/oby.20123

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