Skip navigation
Skip navigation

Molecular Cloning of Mouse Amino Acid Transport System B 0 , a Neutral Amino Acid Transporter Related to Hartnup Disorder

Broer, Angelika; Klingel, Karen; Kowalczuk, Sonja; Rasko, John Edward; Cavanaugh, Juleen; Broer, Stefan

Description

Resorption of amino acids in kidney and intestine is mediated by transporters, which prefer groups of amino acids with similar physico-chemical properties. It is generally assumed that most neutral amino acids are transported across the apical membrane of epithelial cells by system B 0. Here we have characterized a novel member of the Na +-dependent neurotransmitter transporter family (B0AT1) isolated from mouse kidney, which shows all properties of system B0. Flux experiments showed that the...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
URI: http://hdl.handle.net/1885/77672
Source: Journal of Biological Chemistry
DOI: 10.1074/jbc.M400904200

Download

There are no files associated with this item.


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator