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Why the Properties of Proteins in Salt Solutions Follow a Hofmeister Series

Bostrom, Mathias Anders; Williams, David; Ninham, Barry

Description

The physical properties of hen-egg-white lysozyme, and other globular protein, in aqueous solutions depend in a complicated and unexplained way on pH, salt type and salt concentration. One important and previously neglected source of ion specificity is the ionic dispersion potential that acts between each ion and the protein. We present model calculations, performed within a modified ion-specific double layer theory, that demonstrate the large effect of including these ionic dispersion...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
URI: http://hdl.handle.net/1885/77653
Source: Current Opinion in Colloid and Interface Science
DOI: 10.1016/j.cocis.2004.05.001

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