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Measuring environmental factors can enhance the search for disease causing genes?

Dwyer, Terence; Ponsonby, Anne-Louise; Stankovich, James; Blizzard, Leigh; Easteal, Simon

Description

The value of the concurrent measurement of environmental factors in studies aimed at the discovery of disease causing genes has been questioned on the grounds that such an approach fails to increase study power. This report discusses the issue and shows with examples from the recent literature that the examination of a gene disease association within an environmental subgroup can provide enhanced opportunities for detecting gene effects. The concurrent collection of environmental as well as...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
URI: http://hdl.handle.net/1885/77496
Source: Journal of Epidemiology and Community Health
DOI: 10.1136/jech.2003.012971

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