Acute Human Self-Poisoning with the N-Phenylpyrazole Insecticide Fipronil - a GABA(A) - Gated Chloride Channel Blocker
-
Altmetric Citations
Mohammed, Fahim; Senarathna, Lalith; Percy, Adrian; Abeyewardene, Manel; Eaglesham, Geoffrey; Cheng, Ron; Azhar, Shifa; Hittarage, Ariyasena; Di Stasio, Robert; Sheriff, M H Rezvi; Davies, Willie; Buckley, Nicholas; Eddleston, Michael
Description
Objective: Fipronil, a broad spectrum N-phenylpyrazole insecticide that inhibits GABAA-gated chloride channels, has been in use since the mid-199Os. A high affinity for insect compared to mammalian GABA receptors results in lower animal toxicity than other insecticides blocking this channel. To date, only two accidental cases of fipronil poisoning in humans have been published. Case Series: We report seven patients with fipronil self-poisoning seen prospectively in Sri Lanka together with...[Show more]
Collections | ANU Research Publications |
---|---|
Date published: | 2004 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/77260 |
Source: | Clinical Toxicology (Taylor & Francis) |
DOI: | 10.1081/CLT-200041784 |
Download
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 19 May 2020/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator