Sangalli, M; McLean, Allan; Peek, M; Rivory, L.; Le Couteur, D
In order to estimate the placental barrier to gas transfer, a novel carbon monoxide (CO) wash-in method was used to estimate the permeability-surface area (PS) product for the transfer of gas across the foetal circulation in the perfused human term placenta. The PS product for CO was 0.0096 ± 0.006 ml/s/g or 0.012 ± 0.007 ml/s/g using compartmental or Crone-Renkin analysis, respectively. Using this result and a published estimate of the placental capillary surface area, the permeability...[Show more]
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.