Multiple steps of phosphorylation of activated rhodopsin can account for the reproducibility of vertebrate rod single-photon responses
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Hamer, Russell D; Nicholas, S C; Tranchina, D; Liebman, P; Lamb, Trevor
Description
Single-photon responses (SPRs) in vertebrate rods are considerably less variable than expected if isomerized rhodopsin (R*) inactivated in a single, memoryless step, and no other variability-reducing mechanisms were available. We present a new stochastic
dc.contributor.author | Hamer, Russell D | |
---|---|---|
dc.contributor.author | Nicholas, S C | |
dc.contributor.author | Tranchina, D | |
dc.contributor.author | Liebman, P | |
dc.contributor.author | Lamb, Trevor | |
dc.date.accessioned | 2015-12-13T22:37:45Z | |
dc.identifier.issn | 0022-1295 | |
dc.identifier.uri | http://hdl.handle.net/1885/77233 | |
dc.description.abstract | Single-photon responses (SPRs) in vertebrate rods are considerably less variable than expected if isomerized rhodopsin (R*) inactivated in a single, memoryless step, and no other variability-reducing mechanisms were available. We present a new stochastic | |
dc.publisher | Rockefeller University Press | |
dc.source | Journal of General Physiology | |
dc.subject | Keywords: rhodopsin; animal cell; animal tissue; article; DNA modification; Monte Carlo method; mouse; nonhuman; phototransduction; protein phosphorylation; retina rod; stochastic model; vertebrate; Adenosine Triphosphate; Animals; Biotransformation; Calcium Signal Multiple phosphorylation; Phototransduction; Rod responses; Single-photon response reproducibility; Stochastic model | |
dc.title | Multiple steps of phosphorylation of activated rhodopsin can account for the reproducibility of vertebrate rod single-photon responses | |
dc.type | Journal article | |
local.description.notes | Imported from ARIES | |
local.description.refereed | Yes | |
local.identifier.citationvolume | 122 | |
dc.date.issued | 2003 | |
local.identifier.absfor | 110906 - Sensory Systems | |
local.identifier.ariespublication | MigratedxPub6129 | |
local.type.status | Published Version | |
local.contributor.affiliation | Hamer, Russell D, Smith-Kettlewell Eye Institute | |
local.contributor.affiliation | Nicholas, S C, Smith-Kettlewell Eye Institute | |
local.contributor.affiliation | Tranchina, D, New York University | |
local.contributor.affiliation | Liebman, P, University of Pennsylvania | |
local.contributor.affiliation | Lamb, Trevor, College of Medicine, Biology and Environment, ANU | |
local.description.embargo | 2037-12-31 | |
local.bibliographicCitation.issue | 4 | |
local.bibliographicCitation.startpage | 419 | |
local.bibliographicCitation.lastpage | 444 | |
local.identifier.doi | 10.1085/jgp.200308832 | |
dc.date.updated | 2015-12-11T09:38:26Z | |
local.identifier.scopusID | 2-s2.0-0141919837 | |
Collections | ANU Research Publications |
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