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Effects of pentobarbital on GABA-activated currents in acutely-isolated rat dentate gyrus granule neurons

Lim, Michelle; Lindquist, C E L; Birnir, Bryndis

Description

Granule neurons from the rat dentate gyrus were acutely isolated and whole-cell currents recorded. Maximal enhancement of 7 μM γ-aminobutyric acid (GABA; EC30) evoked currents was obtained with 100 μM pentobarbital where the peak-current was 2.1±0.2 o

dc.contributor.authorLim, Michelle
dc.contributor.authorLindquist, C E L
dc.contributor.authorBirnir, Bryndis
dc.date.accessioned2015-12-13T22:37:40Z
dc.identifier.issn0304-3940
dc.identifier.urihttp://hdl.handle.net/1885/77198
dc.description.abstractGranule neurons from the rat dentate gyrus were acutely isolated and whole-cell currents recorded. Maximal enhancement of 7 μM γ-aminobutyric acid (GABA; EC30) evoked currents was obtained with 100 μM pentobarbital where the peak-current was 2.1±0.2 o
dc.publisherElsevier
dc.sourceNeuroscience Letters
dc.subjectKeywords: 4 aminobutyric acid; 4 aminobutyric acid A receptor; ion channel; pentobarbital; animal tissue; article; concentration response; controlled study; dentate gyrus; drug effect; granule cell; nerve cell; nerve potential; nonhuman; patch clamp; priority journ ?-aminobutyric acidA; Barbiturates; Hippocampus; Inhibition; Ion channel; Receptor
dc.titleEffects of pentobarbital on GABA-activated currents in acutely-isolated rat dentate gyrus granule neurons
dc.typeJournal article
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.citationvolume353
dc.date.issued2003
local.identifier.absfor110999 - Neurosciences not elsewhere classified
local.identifier.ariespublicationMigratedxPub6090
local.type.statusPublished Version
local.contributor.affiliationLim, Michelle, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationLindquist, C E L, Lund University
local.contributor.affiliationBirnir, Bryndis, College of Medicine, Biology and Environment, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.startpage139
local.bibliographicCitation.lastpage142
local.identifier.doi10.1016/j.neulet.2003.09.025
dc.date.updated2015-12-11T09:37:41Z
local.identifier.scopusID2-s2.0-0345096615
CollectionsANU Research Publications

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