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Age-related pseudocapillarization of the human liver

McLean, Allan J; Cogger, Victoria; Chong, Guan; Warren, Alessandra; Markus, Astrid; Dahlstrom, Jane; Le Couteur, David


Age-related changes in liver function are important because they may promote susceptibility to adverse drug reactions, neurotoxicity, atherosclerosis, and other important diseases in older people. Age-related changes in the rat hepatic sinusoidal endothelium, termed pseudocapillarization, have been described recently and these may contribute to hepatic impairment. The present study has examined surgical and post-mortem specimens with immunohistochemistry and transmission electron microscopy to...[Show more]

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: Journal of Pathology
DOI: 10.1002/path.1328


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