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Antiphospholipid antibodies and stroke in Down syndrome

Gatenby, Paul; Tuck, Roger; Andrews, C; O'Neil, R

Description

Two patients with Down syndrome and the primary antiphospholipid antibody are described. One patient had a vasculopathy similar to that previously described as Moyamoya. Down syndrome is characterized by immune defects including a tendency to autoimmune phenomena. This report extends the scope of these observations and particularly draws out the potential role of antiphospholipid antibodies. Indeed antiphospholipid antibodies may well explain the well-known association of Down syndrome and...[Show more]

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
URI: http://hdl.handle.net/1885/77027
Source: LUPUS
DOI: 10.1191/0961203303lu240cr

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