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Clinical description of a completed outbreak of SARS in Vietnam, February-May 2003

Vu, Hoang; Leitmeyer, Katrin; Le, Dang; Miller, Megge; Mguyen, Quang; Uyeki, Timothy; Reynolds, Mary G; Aagesen, Jesper; Nicholson, K G; Vu, Quang; Bach, Huy; Plant, Aileen

Description

We investigated the clinical manifestations and course of all probable severe acute respiratory syndrome (SARS) patients in the Vietnam outbreak. Probable SARS cases were defined by using the revised World Health Organization criteria. We systematically reviewed medical records and undertook descriptive statistical analyses. All 62 patients were hospitalized. On admission, the most prominent symptoms were malaise (82.3%) and fever (79.0%). Cough, chest pain, and shortness of breath were present...[Show more]

dc.contributor.authorVu, Hoang
dc.contributor.authorLeitmeyer, Katrin
dc.contributor.authorLe, Dang
dc.contributor.authorMiller, Megge
dc.contributor.authorMguyen, Quang
dc.contributor.authorUyeki, Timothy
dc.contributor.authorReynolds, Mary G
dc.contributor.authorAagesen, Jesper
dc.contributor.authorNicholson, K G
dc.contributor.authorVu, Quang
dc.contributor.authorBach, Huy
dc.contributor.authorPlant, Aileen
dc.date.accessioned2015-12-13T22:36:50Z
dc.date.available2015-12-13T22:36:50Z
dc.identifier.issn1080-6040
dc.identifier.urihttp://hdl.handle.net/1885/76963
dc.description.abstractWe investigated the clinical manifestations and course of all probable severe acute respiratory syndrome (SARS) patients in the Vietnam outbreak. Probable SARS cases were defined by using the revised World Health Organization criteria. We systematically reviewed medical records and undertook descriptive statistical analyses. All 62 patients were hospitalized. On admission, the most prominent symptoms were malaise (82.3%) and fever (79.0%). Cough, chest pain, and shortness of breath were present in approximately one quarter of the patients; 79.0% had lymphopenia; 40.3% had thrombocytopenia; 19.4% had leukopenia; and 75.8% showed changes on chest radiograph. Fever developed on the first day of illness onset, and both respiratory symptoms and radiographic changes occurred on day 4. On average, maximal radiographic changes were observed on day 10, and fevers subsided by day 13. Symptoms on admission were nonspecific, although fever, malaise, and lymphopenia were common. The complications of SARS included invasive intubation and ventilation (11.3%) and death (9.7%).
dc.publisherUS National Centre for Infectious Diseases
dc.sourceEmerging Infectious Diseases
dc.subjectKeywords: aminoglycoside antibiotic agent; antibiotic agent; antivirus agent; beta lactam antibiotic; macrolide; oseltamivir; quinoline derived antiinfective agent; ribavirin; steroid; tetracycline; adult; aged; article; cause of death; clinical feature; endotrache
dc.titleClinical description of a completed outbreak of SARS in Vietnam, February-May 2003
dc.typeJournal article
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.citationvolume10
dc.date.issued2004
local.identifier.absfor111706 - Epidemiology
local.identifier.ariespublicationMigratedxPub5797
local.type.statusPublished Version
local.contributor.affiliationVu, Hoang, Hanoi French Hospital
local.contributor.affiliationLeitmeyer, Katrin, Hanoi French Hospital
local.contributor.affiliationLe, Dang, Hanoi French Hospital
local.contributor.affiliationMiller, Megge, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationMguyen, Quang, Hanoi French Hospital
local.contributor.affiliationUyeki, Timothy, Hanoi French Hospital
local.contributor.affiliationReynolds, Mary G, Hanoi French Hospital
local.contributor.affiliationAagesen, Jesper, Hanoi French Hospital
local.contributor.affiliationNicholson, K G, Hanoi French Hospital
local.contributor.affiliationVu, Quang, Hanoi French Hospital
local.contributor.affiliationBach, Huy, Hanoi French Hospital
local.contributor.affiliationPlant, Aileen, Hanoi French Hospital
local.bibliographicCitation.issue2
local.bibliographicCitation.startpage334
local.bibliographicCitation.lastpage38
dc.date.updated2015-12-11T09:33:46Z
local.identifier.scopusID2-s2.0-10744229623
CollectionsANU Research Publications

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