Skip navigation
Skip navigation

Enhanced effect of dopaminergic stimulation on prepulse inhibition in mice deficient in the alpha subunit of G(z)

van den Buuse, Maarten; Martin, Sally; Brosda, J; Leck, Kwong-Joo; Matthaei, Klaus; Hendry, Ian

Description

Rationale: Gz is a member of the Gi G protein family associated with dopamine D2-like receptors; however, its functions remain relatively unknown. The aim of the present study was to investigate prepulse inhibition (PPI) of acoustic startle, locomotor hyperactivity and dopamine D2 receptor binding in mice deficient in the α subunit of Gz. Methods: We used automated startle boxes to assess startle and PPI after treatment with saline, amphetamine, apomorphine or MK-801. We used photocell cages to...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
URI: http://hdl.handle.net/1885/76630
Source: Psychopharmacology
DOI: 10.1007/s00213-005-0181-6

Download

File Description SizeFormat Image
01_van den Buuse_Enhanced_effect_of_2005.pdf277.15 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  23 August 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator