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The recombinant dihydropyridine receptor II-III loop and partly structured C region peptides modify cardiac ryanodine receptor activity

Dulhunty, Angela; Karunasekara, Yamuna; Curtis, Suzanne; Harvey, Peta; Board, Philip; Casarotto, Marco


A physical association between the II-III loop of the DHPR (dihydropryidine receptor) and the RyR (ryanodine receptor) is essential for excitation-contraction coupling in skeletal, but not cardiac, muscle. However, peptides corresponding to a part of the

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
Source: Biochemical Journal
DOI: 10.1042/BJ20041152


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