Calcium-activated potassium channels: multiple contributions to neuronal function
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Faber, Elizabeth (Louise); Sah, Pankaj
Description
Calcium-activated potassium channels are a large family of potassium channels that are found throughout the central nervous system and in many other cell types. These channels are activated by rises in cytosolic calcium largely in response to calcium influx via voltage-gated calcium channels that open during action potentials. Activation of these potassium channels is involved in the control of a number of physiological processes from the firing properties of neurons to the control of...[Show more]
dc.contributor.author | Faber, Elizabeth (Louise) | |
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dc.contributor.author | Sah, Pankaj | |
dc.date.accessioned | 2015-12-13T22:34:58Z | |
dc.date.available | 2015-12-13T22:34:58Z | |
dc.identifier.issn | 1073-8584 | |
dc.identifier.uri | http://hdl.handle.net/1885/76372 | |
dc.description.abstract | Calcium-activated potassium channels are a large family of potassium channels that are found throughout the central nervous system and in many other cell types. These channels are activated by rises in cytosolic calcium largely in response to calcium influx via voltage-gated calcium channels that open during action potentials. Activation of these potassium channels is involved in the control of a number of physiological processes from the firing properties of neurons to the control of transmitter release. These channels form the target for modulation for a range of neurotransmitters and have been implicated in the pathogenesis of neurological and psychiatric disorders. Here the authors summarize the varieties of calcium-activated potassium channels present in central neurons and their defining molecular and biophysical properties. | |
dc.publisher | Sage Science Press | |
dc.source | The Neuroscientist | |
dc.subject | Keywords: calcium; calcium activated potassium channel; calcium channel; action potential; calcium transport; central nervous system; channel gating; nerve function; pathogenesis; priority journal; review; Aging; Animals; Brain Diseases; Calcium; Central Nervous Sy Accommodation; AHP; SAHP; SK channel | |
dc.title | Calcium-activated potassium channels: multiple contributions to neuronal function | |
dc.type | Journal article | |
local.description.notes | Imported from ARIES | |
local.description.refereed | Yes | |
local.identifier.citationvolume | 9 | |
dc.date.issued | 2003 | |
local.identifier.absfor | 110903 - Central Nervous System | |
local.identifier.ariespublication | MigratedxPub5186 | |
local.type.status | Published Version | |
local.contributor.affiliation | Faber, Elizabeth (Louise), College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Sah, Pankaj, College of Medicine, Biology and Environment, ANU | |
local.bibliographicCitation.issue | 3 | |
local.bibliographicCitation.startpage | 181 | |
local.bibliographicCitation.lastpage | 194 | |
local.identifier.doi | 10.1177/1073858403009003011 | |
dc.date.updated | 2015-12-11T09:25:07Z | |
local.identifier.scopusID | 2-s2.0-0038175132 | |
Collections | ANU Research Publications |
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