Teng, Rongwei; Lehane, Adele; Winterberg, Markus; Shafik, Sarah; Summers, Robert; Martin, Rowena; Van Schalkwyk, Donelly; Junankar, Pauline; Kirk, Kiaran
Although efforts to understand the basis for inter-strain phenotypic variation in the most virulent malaria species, Plasmodium falciparum, have benefited from advances in genomic technologies, there have to date been few metabolomic studies of this parasite. Using 1H-NMR spectroscopy, we have compared the metabolite profiles of red blood cells infected with different P. falciparum strains. These included both chloroquine-sensitive and chloroquine-resistant strains, as well as transfectant...[Show more]
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