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1H-NMR metabolite profiles of different strains of Plasmodium falciparum

Teng, Rongwei; Lehane, Adele; Winterberg, Markus; Shafik, Sarah; Summers, Robert; Martin, Rowena; Van Schalkwyk, Donelly; Junankar, Pauline; Kirk, Kiaran

Description

Although efforts to understand the basis for inter-strain phenotypic variation in the most virulent malaria species, Plasmodium falciparum, have benefited from advances in genomic technologies, there have to date been few metabolomic studies of this parasite. Using 1H-NMR spectroscopy, we have compared the metabolite profiles of red blood cells infected with different P. falciparum strains. These included both chloroquine-sensitive and chloroquine-resistant strains, as well as transfectant...[Show more]

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
URI: http://hdl.handle.net/1885/76217
Source: Bioscience Reports
DOI: 10.1042/BSR20140134

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