Skip navigation
Skip navigation

Integron-associated mobile gene cassettes code for folded proteins: the structure of Bal32a, a new member of the adaptable α+β barrel family

Robinson, Andrew; Wu, Peter; Harrop, Stephen; Schaeffer, Patrick; Dosztanyi, Zsuzsanna; Gillings, Michael; Holmes, Andrew; Nevalainen, K M Helena; Stokes, Harold W; Dixon, Nicholas; Curmi, Paul; Mabbutt, Bridget; Otting, Gottfried

Description

The wide-ranging physiology and large genetic variability observed for prokaryotes is largely attributed, not to the prokaryotic genome itself, but rather to mechanisms of lateral gene transfer. Cassette PCR has been used to sample the integron/gene cassette metagenome from different natural environments without laboratory cultivation of the host organism, and without prior knowledge of any target protein sequence. Since over 90% of cassette genes are unrelated to any sequence in the current...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
URI: http://hdl.handle.net/1885/76088
Source: Journal of Molecular Biology
DOI: 10.1016/j.jmb.2004.12.035

Download

File Description SizeFormat Image
01_Robinson_Integron-associated_mobile_2005.pdf834.49 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  27 November 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator