Skip navigation
Skip navigation

Total synthesis of sordaricin

Mander, Lewis; Thomson, Regan


(Chemical Equation Presented) An enantioconvergent total synthesis of sordaricin (3), the diterpene aglycon of an important class of antifungal compounds, is described. Two approaches were explored, the first of which utilized a possible biogenetic intramolecular [4 + 2] cycloaddition to form the complete carbon skeleton of the target molecule as a single regioisomer 30. A second approach employed a tandem cycloreversion/ intramolecular [4 + 2] cycloaddition process to afford not only the...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
Source: Journal of Organic Chemistry
DOI: 10.1021/jo048199b


There are no files associated with this item.

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator