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Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha

Fontes, Marcos; Teh, Trazel; Jans, David A; Brinkworth, Ross I; Kobe, Bostjan


Importin-α is the nuclear import receptor that recognizes cargo proteins carrying conventional basic monopartite and bipartite nuclear localization sequences (NLSs) and facilitates their transport into the nucleus. Bipartite NLSs contain two clusters of

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: Journal of Biological Chemistry
DOI: 10.1074/jbc.M303275200


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