Skip navigation
Skip navigation

Discovery and refinement of muscle weight QTLs in B6 X D2 advanced intercross mice

Carbonetto, P; Cheng, Riyan; Gyekis, J P; Parker, C C; Blizard, David A; Palmer, A A; Lionikas, Arimantas


The genes underlying variation in skeletal muscle mass are poorly understood. Although many quantitative trait loci (QTLs) have been mapped in crosses of mouse strains, the limited resolution inherent in these conventional studies has made it difficult to reliably pinpoint the causal genetic variants. The accumulated recombination events in an advanced intercross line (AIL), in which mice from two inbred strains are mated at random for several generations, can improve mapping resolution. We...[Show more]

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
Source: Physiological Genomics
DOI: 10.1152/physiolgenomics.00055.2014


File Description SizeFormat Image
01_Carbonetto_Discovery_and_refinement_of_2014.pdf1.17 MBAdobe PDF    Request a copy

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator