Skip navigation
Skip navigation
A change is coming. Click to see a sneak peek of the new Open Research Repository.

Studies with the Plasmodium falciparum hexokinase reveal that PfHT limits the rate of glucose entry into glycolysis

Request a Copy

link to publisher version

  • Altmetric Citations

Tjhin, Erick; Staines, Henry M.; Van Schalkwyk, Donelly; Krishna, Sanjeev; Saliba, Kevin

Description

To characterise plasmodial glycolysis, we generated two transgenic Plasmodium falciparum lines, one expressing P. falciparum hexokinase (PfHK) tagged with GFP (3D7-PfHKGFP) and another overexpressing native PfHK (3D7-PfHK+). Contrary to previous reports,

dc.contributor.authorTjhin, Erick
dc.contributor.authorStaines, Henry M.
dc.contributor.authorVan Schalkwyk, Donelly
dc.contributor.authorKrishna, Sanjeev
dc.contributor.authorSaliba, Kevin
dc.date.accessioned2015-12-13T22:30:26Z
dc.identifier.issn0014-5793
dc.identifier.urihttp://hdl.handle.net/1885/74838
dc.description.abstractTo characterise plasmodial glycolysis, we generated two transgenic Plasmodium falciparum lines, one expressing P. falciparum hexokinase (PfHK) tagged with GFP (3D7-PfHKGFP) and another overexpressing native PfHK (3D7-PfHK+). Contrary to previous reports,
dc.publisherElsevier
dc.sourceFEBS Letters
dc.subjectKeywords: deoxyglucose; glucose; glucose transporter; hexokinase; article; cellular distribution; controlled study; cytosol; enzyme activity; glucose transport; glycolysis; nonhuman; Plasmodium falciparum; priority journal; transgenic organism; Glucose; Hexokinase; Glucose; Hexokinase; Hexose transport; Malaria; Plasmodium
dc.titleStudies with the Plasmodium falciparum hexokinase reveal that PfHT limits the rate of glucose entry into glycolysis
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume587
dc.date.issued2013
local.identifier.absfor060100 - BIOCHEMISTRY AND CELL BIOLOGY
local.identifier.ariespublicationf5625xPUB4330
local.type.statusPublished Version
local.contributor.affiliationTjhin, Erick, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationStaines, Henry M, University of London
local.contributor.affiliationVan Schalkwyk, Donelly, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationKrishna, Sanjeev, St. George's Hospital Medical School
local.contributor.affiliationSaliba, Kevin, College of Medicine, Biology and Environment, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.issue19
local.bibliographicCitation.startpage3182
local.bibliographicCitation.lastpage3187
local.identifier.doi10.1016/j.febslet.2013.07.052
dc.date.updated2016-02-24T09:23:58Z
local.identifier.scopusID2-s2.0-84884291474
local.identifier.thomsonID000324472200004
CollectionsANU Research Publications

Download

File Description SizeFormat Image
01_Tjhin_Studies_with_the_Plasmodium_2013.pdf840.33 kBAdobe PDF    Request a copy
Show simple item record


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  17 November 2022/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator