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Isolation of chromosomal regions controlling intersex development in a marsupial

Santucciu, C; Gruetzner, Frank; Carvalho-Silva, D; Graves, Jennifer


A marsupial (Sminthopsis douglasi) with bilateral intersexuality had a hemiscrotum on the right side and a hemi-pouch with nipples on the left. A normal female karyotype (2n = 14, XX) was present in cells from the right (male) side, while cells from the left (female) side initially had a female karyotype plus two dot-like chromosomes (2n = 14, XX + 2B). It is proposed that the dots represented a region deleted from the X chromosome that contains the "pouch-mammary/scrotum" (PMS) switch gene...[Show more]

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: Cytogenetic and Genome Research
DOI: 10.1159/000074341


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