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Pioglitazone acutely reduces energy metabolism and insulin secretion in rats

Lamontagne, Julien; Jalbert-Arsenault, Élise; Pepin, Emilie; Peyot, Marie-Line; Ruderman, Neil; Nolan, Christopher; Joly, Erik; Madiraju, Murthy S R; Poitout, Vincent; Prentki, Marc

Description

Our objective was to determine if the insulin-sensitizing drug pioglitazone acutely reduces insulin secretion and causes metabolic deceleration in vivo independently of change in insulin sensitivity. We assessed glucose homeostasis by hyperinsulinemiceugl

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
URI: http://hdl.handle.net/1885/74445
Source: Diabetes
DOI: 10.2337/db12-0428

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