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A Novel Functional Epitope Formed by Domains 1 and 4 of the Human Common beta -Subunit Is Involved in Receptor Activation by Granulocyte Macrophage Colony-stimulating Factor and Interleukin 5*

Murphy, James; Ford, Sally; Wiedemann, Ursula; Carr, Paul D; Ollis, David; Young, Ian


The receptors for human interleukins 3 and 5 and granulocyte macrophage colony-stimulating factor are composed of ligand-specific α-subunits and a common β-subunit (βc), the major signaling entity. The way in which βc interacts with ligands in the res

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: Journal of Biological Chemistry
DOI: 10.1074/jbc.M211664200


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