The dynamics of GII.4 Norovirus in Ho Chi Minh City, Vietnam
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My, Phan Vu Tra; Lam, Ha Minh; Thompson, Corinne; Phuc, Hoang Le; Tuyet, Pham Thi Ngoc; Vinh, Ha; Hoang, Nguyen Van Minh; Minh, PhamVan; Vinh, Nguyen Thanh; Thuy, Cao Thu; Clements, Archie
Description
Norovirus (NoV) is a major cause of epidemic gastroenteritis in industrialized countries, yet the epidemiological significance of NoV in industrializing countries remains poorly understood. The spatiotemporal distribution of NoV genotypes identified in 2054 enrolled children was investigated between May 2009 and December 2010, in Ho Chi Minh City (HCMC), Vietnam. A total of 315 NoV extracted from stool samples were genotyped and GPS mapped to their source. Genogroup II NoV, particularly GII.4,...[Show more]
dc.contributor.author | My, Phan Vu Tra | |
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dc.contributor.author | Lam, Ha Minh | |
dc.contributor.author | Thompson, Corinne | |
dc.contributor.author | Phuc, Hoang Le | |
dc.contributor.author | Tuyet, Pham Thi Ngoc | |
dc.contributor.author | Vinh, Ha | |
dc.contributor.author | Hoang, Nguyen Van Minh | |
dc.contributor.author | Minh, PhamVan | |
dc.contributor.author | Vinh, Nguyen Thanh | |
dc.contributor.author | Thuy, Cao Thu | |
dc.contributor.author | Clements, Archie | |
dc.date.accessioned | 2015-12-13T22:28:44Z | |
dc.identifier.issn | 1567-1348 | |
dc.identifier.uri | http://hdl.handle.net/1885/74334 | |
dc.description.abstract | Norovirus (NoV) is a major cause of epidemic gastroenteritis in industrialized countries, yet the epidemiological significance of NoV in industrializing countries remains poorly understood. The spatiotemporal distribution of NoV genotypes identified in 2054 enrolled children was investigated between May 2009 and December 2010, in Ho Chi Minh City (HCMC), Vietnam. A total of 315 NoV extracted from stool samples were genotyped and GPS mapped to their source. Genogroup II NoV, particularly GII.4, were predominant, and the GII.4 strains could be subgrouped into GII.4-2006b (Minerva) and GII.4-2010 (New Orleans) variants. There was no spatiotemporal structure among the endemic GII strains; yet a significant spatiotemporal signal corresponding with the novel introduction of GII.4-2010 variant was detected. These data show that NoV GII.4 variants are highly endemic in HCMC and describe a scenario of rapid NoV strain replacement occurring in HCMC in early 2010. | |
dc.publisher | Elsevier BV | |
dc.source | Infection, Genetics and Evolution | |
dc.subject | Keywords: acute diarrhea; article; asymptomatic disease; child; controlled study; feces analysis; genotype; human; infant; major clinical study; microbial population dynamics; nonhuman; Norovirus; norovirus infection; nucleotide sequence; preschool child; priority Cluster; GII.4; Norovirus; Phylogenetic; Spatial; Temporal | |
dc.title | The dynamics of GII.4 Norovirus in Ho Chi Minh City, Vietnam | |
dc.type | Journal article | |
local.description.notes | Imported from ARIES | |
local.identifier.citationvolume | 18 | |
dc.date.issued | 2013 | |
local.identifier.absfor | 060400 - GENETICS | |
local.identifier.ariespublication | U3488905xPUB4068 | |
local.type.status | Published Version | |
local.contributor.affiliation | My, Phan Vu Tra, Oxford University Clinical Research Unit | |
local.contributor.affiliation | Lam, Ha Minh, Oxford University Clinical Research Unit | |
local.contributor.affiliation | Thompson, Corinne, Oxford University Clinical Research Unit | |
local.contributor.affiliation | Phuc, Hoang Le, Childrens Hospital | |
local.contributor.affiliation | Tuyet, Pham Thi Ngoc, Childrens Hospital 2 | |
local.contributor.affiliation | Vinh, Ha, Hospital for Tropical Diseases | |
local.contributor.affiliation | Hoang, Nguyen Van Minh, Oxford University Clinical Research Unit | |
local.contributor.affiliation | Minh, PhamVan, Oxford University Clinical Research Unit | |
local.contributor.affiliation | Vinh, Nguyen Thanh, Oxford University Clinical Research Unit | |
local.contributor.affiliation | Thuy, Cao Thu, Oxford University Clinical Research Unit | |
local.contributor.affiliation | Clements, Archie, College of Medicine, Biology and Environment, ANU | |
local.description.embargo | 2037-12-31 | |
local.bibliographicCitation.startpage | 335 | |
local.bibliographicCitation.lastpage | 343 | |
local.identifier.doi | 10.1016/j.meegid.2013.04.014 | |
dc.date.updated | 2016-02-24T10:05:12Z | |
local.identifier.scopusID | 2-s2.0-84880305870 | |
Collections | ANU Research Publications |
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