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Growth factor TGF- β induces intestinal epithelial cell (IEC-6) differentiation: MiR-146b as a regulatory component in the negative feedback loop

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Liao, Yalin; Zhang, Man; Lonnerdal, Bo

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TGF-β is a potent pleiotropic factor that promotes small intestinal cell differentiation. The role of microRNAs in the TGF-β induction of intestinal epithelial phenotype is largely unknown. We hypothesized that microRNAs are functionally involved in TGF

dc.contributor.authorLiao, Yalin
dc.contributor.authorZhang, Man
dc.contributor.authorLonnerdal, Bo
dc.date.accessioned2015-12-13T22:28:32Z
dc.identifier.issn1865-3499
dc.identifier.urihttp://hdl.handle.net/1885/74245
dc.description.abstractTGF-β is a potent pleiotropic factor that promotes small intestinal cell differentiation. The role of microRNAs in the TGF-β induction of intestinal epithelial phenotype is largely unknown. We hypothesized that microRNAs are functionally involved in TGF
dc.publisherSpringer
dc.sourceGenes & Nutrition
dc.subjectKeywords: alkaline phosphatase; microRNA; microRNA 146b; microsomal aminopeptidase; mitogen activated protein kinase 1; mitogen activated protein kinase 3; protein SIAH2; Smad7 protein; transforming growth factor beta; ubiquitin protein ligase E3; unclassified drug Differentiation; IEC-6 cell; microRNA array; miR-146b; SIAH2; TGF-ß
dc.titleGrowth factor TGF- β induces intestinal epithelial cell (IEC-6) differentiation: MiR-146b as a regulatory component in the negative feedback loop
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume8
dc.date.issued2013
local.identifier.absfor060407 - Genome Structure and Regulation
local.identifier.ariespublicationf5625xPUB4029
local.type.statusPublished Version
local.contributor.affiliationLiao, Yalin, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationZhang, Man, University of California
local.contributor.affiliationLonnerdal, Bo, University of California
local.description.embargo2037-12-31
local.bibliographicCitation.issue1
local.bibliographicCitation.startpage69
local.bibliographicCitation.lastpage78
local.identifier.doi10.1007/s12263-012-0297-3
dc.date.updated2016-02-24T09:20:07Z
local.identifier.scopusID2-s2.0-84872395266
local.identifier.thomsonID000313019100007
CollectionsANU Research Publications

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