A Role for Macrophage Inflammatory Protein-3(Beta Symbol)/CC chemokine Ligand 20 in Immune Priming During T Cell-Mediated Inflammation of the Central Nervous System
Chemokines are a family of cytokines that exhibit selective chemoattractant properties for target leukocytes and play a significant role in leukocyte migration. In this study, we have investigated the role of the C-C chemokine, macrophage inflammatory protein (MIP)-3α/CC chemokine ligand 20, in the pathogenesis of experimental autoimmune encephalomyelitis (EAE), a model of T cell-dependent inflammation. Expression in the CNS of MIP-3α, as determined by RT-PCR, increased in a time-dependent...[Show more]
|Collections||ANU Research Publications|
|Source:||Journal of Immunology|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.