Skip navigation
Skip navigation

Platelets, selectins, and the control of tumor metastasis

Coupland, Lucy; Chong, Beng; Parish, Christopher

Description

The significant role of platelets and P-selectin in assisting tumor cell metastasis to the lungs has been frequently reported and reviewed. However, evidence recently has come to light on other pro-metastatic mechanisms of platelets beyond that of tumor cell protection from immune cell attack and aiding extravasation, such as promoting epithelial to mesenchymal transition in tumor cells and conveying signals from the primary tumor to distant tissues that optimize conditions for metastasis....[Show more]

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
URI: http://hdl.handle.net/1885/74084
Source: Seminars in Oncology
DOI: 10.1053/j.seminoncol.2014.04.003

Download

File Description SizeFormat Image
01_Coupland_Platelets,_selectins,_and_the_2014.pdf1.47 MBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator