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Smchd1 regulates a subset of autosomal genes subject to monoallelic expression in addition to being critical for X inactivation

Mould, Arne; Pang, Zhenyi; Pakusch, Miha; Tonks, Ian D.; Stark, Mitchell; Carrie, Dianne; Mukhopadhyay, Pamela; Seidel, Annica; Ellis, Jonathan J.; Deakin, Janine; Wakefield, Matthew; Krause, Lutz; Blewitt, Marnie E; Kay, Graham F.

Description

Background: Smchd1 is an epigenetic modifier essential for X chromosome inactivation: female embryos lacking Smchd1 fail during midgestational development. Male mice are less affected by Smchd1-loss, with some (but not all) surviving to become fertile adu

dc.contributor.authorMould, Arne
dc.contributor.authorPang, Zhenyi
dc.contributor.authorPakusch, Miha
dc.contributor.authorTonks, Ian D.
dc.contributor.authorStark, Mitchell
dc.contributor.authorCarrie, Dianne
dc.contributor.authorMukhopadhyay, Pamela
dc.contributor.authorSeidel, Annica
dc.contributor.authorEllis, Jonathan J.
dc.contributor.authorDeakin, Janine
dc.contributor.authorWakefield, Matthew
dc.contributor.authorKrause, Lutz
dc.contributor.authorBlewitt, Marnie E
dc.contributor.authorKay, Graham F.
dc.date.accessioned2015-12-13T22:27:33Z
dc.identifier.issn1756-8935
dc.identifier.urihttp://hdl.handle.net/1885/73986
dc.description.abstractBackground: Smchd1 is an epigenetic modifier essential for X chromosome inactivation: female embryos lacking Smchd1 fail during midgestational development. Male mice are less affected by Smchd1-loss, with some (but not all) surviving to become fertile adu
dc.publisherBioMed Central Ltd.
dc.sourceEpigenetics and Chromatin
dc.subjectKeywords: cadherin; cell protein; protocadherin alpha; protocadherin beta; protocadherin gamma; Smchd1 protein; unclassified drug; article; autosomal disorder; biallelic expression; chromosome; CpG island; embryo development; epigenetics; gene cluster; gene disrupt Clustered protocadherins; Genomic imprinting; Monoallelic expression; Smchd1; X inactivation
dc.titleSmchd1 regulates a subset of autosomal genes subject to monoallelic expression in addition to being critical for X inactivation
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume6
dc.date.issued2013
local.identifier.absfor060404 - Epigenetics (incl. Genome Methylation and Epigenomics)
local.identifier.ariespublicationf5625xPUB3918
local.type.statusPublished Version
local.contributor.affiliationMould, Arne, Queensland Institute of Medical Research
local.contributor.affiliationPang, Zhenyi, Queensland Institute of Medical Research
local.contributor.affiliationPakusch, Miha, Walter and Eliza Hall Institute
local.contributor.affiliationTonks, Ian D., Queensland Institute of Medical Research
local.contributor.affiliationStark, Mitchell, Queensland Institute of Medical Research
local.contributor.affiliationCarrie, Dianne, Queensland Institute of Medical Research
local.contributor.affiliationMukhopadhyay, Pamela, Queensland Institute of Medical Research
local.contributor.affiliationSeidel, Annica, Queensland Institute of Medical Research
local.contributor.affiliationEllis, Jonathan J., Queensland Institute of Medical Research
local.contributor.affiliationDeakin, Janine, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationWakefield, Matthew, Walter and Eliza Hall Institute of Medical Research
local.contributor.affiliationKrause, Lutz, Queensland Institute of Medical Research
local.contributor.affiliationBlewitt, Marnie E, University of Sydney
local.contributor.affiliationKay, Graham F., Queensland Institute of Medical Research
local.description.embargo2037-12-31
local.bibliographicCitation.issue19
local.bibliographicCitation.startpage1
local.bibliographicCitation.lastpage16
local.identifier.doi10.1186/1756-8935-6-19
local.identifier.absseo970106 - Expanding Knowledge in the Biological Sciences
dc.date.updated2016-02-24T09:18:54Z
local.identifier.scopusID2-s2.0-84879817115
local.identifier.thomsonID000321520900001
CollectionsANU Research Publications

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