Skip navigation
Skip navigation

Using Deubiquitylating Enzymes as Research Tools

Baker, Rohan; Catanzariti, Ann-Maree; Karunasekara, Yamuna; Soboleva, Tatiana; Sharwood, Robert; Whitney, Spencer; Board, Philip

Description

Ubiquitin is synthesized in eukaryotes as a linear fusion with a normal peptide bond either to itself or to one of two ribosomal proteins and, in the latter case, enhances the yield of these ribosomal proteins and/or their incorporation into the ribosome. Such fusions are cleaved rapidly by a variety of deubiquitylating enzymes. Expression of heterologous proteins as linear ubiquitin fusions has been found to significantly increase the yield of unstable or poorly expressed proteins in either...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Book chapter
URI: http://hdl.handle.net/1885/73843
DOI: 10.1016/S0076-6879(05)98044-0

Download

There are no files associated with this item.


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  23 August 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator