Characterization of the human Omega class glutathione transferase genes and associated polymorphisms
The Omega class glutathione transferases (GSTs) have been identified in many organisms, including human, mouse, rat, pig, Caenorhabditis elegans and Drosophila melanogaster. These GSTs have poor activity with common GST substrates, but exhibit novel glutathione-dependent thioltransferase, dehydroascorbate reductase and monomethylarsonate reductase activities, and modulate Ca2+ release by ryanodine receptors. An investigation of the genomic organization of human GSTO1 identified a second...[Show more]
|Collections||ANU Research Publications|
|Source:||Pharmacogenetics and Genomics|
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