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From glutathione transferase to pore in a CLIC

Cromer, Brett A; Morton, Craig; Board, Philip; Parker, Michael William

Description

Many plasma membrane chloride channels have been cloned and characterized in great detail. In contrast, very little is known about intracellular chloride channels. Members of a novel class of such channels, called the CLICs (chloride intracellular channels), have been identified over the last few years. A striking feature of the CLIC family of ion channels is that they can exist in a water-soluble state as well as a membrane-bound state. A major step forward in understanding the functioning of...[Show more]

CollectionsANU Research Publications
Date published: 2002
Type: Journal article
URI: http://hdl.handle.net/1885/73327
Source: European Biophysics Journal
DOI: 10.1007/s00249-002-0219-1

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