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Nuclear calcium signaling evoked by cholinergic stimulation in hippocampal CA1 pyramidal neurons

Power, John; Sah, Pankaj


The cholinergic system is thought to play an important role in hippocampal-dependent learning and memory. However, the mechanism of action of the cholinergic system in these actions in not well understood. Here we examined the effect of muscarinic receptor stimulation in hippocampal CA1 pyramidal neurons using whole-cell recordings in acute brain slices coupled with high-speed imaging of intracellular calcium. Activation of muscarinic acetylcholine receptors by synaptic stimulation of...[Show more]

CollectionsANU Research Publications
Date published: 2002
Type: Journal article
Source: Journal of Neuroscience


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