Skip navigation
Skip navigation

Alphavirus 6K proteins form ion channels

Melton, Julian; Ewart, Gary; Weir, Ron; Board, Philip; Lee, Eva; Gage, Peter

Description

Ross River virus and Barmah Forest virus are Australian arboviruses of the Alphavirus genus. Features of alphavirus infection include an increased permeability of cells to monovalent cations followed by virion budding. Virally encoded ion channels are thought to have a role in these processes. In this paper, the 6K proteins of Ross River virus and Barmah Forest virus are shown to form cation-selective ion channels in planar lipid bilayers. Using a novel purification method, bacterially...[Show more]

CollectionsANU Research Publications
Date published: 2002
Type: Journal article
URI: http://hdl.handle.net/1885/73116
Source: Journal of Biological Chemistry
DOI: 10.1074/jbc.M207847200

Download

File Description SizeFormat Image
01_Melton_Alphavirus_6K_proteins_form_2002.pdf765.93 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  27 November 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator