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A chemoenzymatic synthesis of the styryllactone (+)-goniodiol from naphthalene

Banwell, Martin; Coster, Mark; Karunaratne, Ochitha; Smith, Jason A

Description

The enantiomerically pure cis-1,2-diol 2, which is obtained by microbial oxidation of naphthalene, has been converted, via a sequence of reactions including oxidative C-C bond cleavage, decarbonylation and ring-closing metathesis steps, into the natural product (+)-goniodiol (1).

CollectionsANU Research Publications
Date published: 2002
Type: Journal article
URI: http://hdl.handle.net/1885/73000
Source: Journal of the Chemical Society, Perkin Transactions 1

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