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Complex structures between the N-type calcium channel (CaV2.2) and I-Conotoxin GVIA predicted via molecular dynamics

Chung, Shin-Ho; Chen, Rong


The N-type voltage-gated Ca2+ channel CaV2.2 is one of the important targets for pain management. ω-Conotoxins isolated from venoms of cone snails, which specifically inhibit CaV2.2, are promising scaffolds for novel analgesics. The inhibitory action of

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
Source: Analytical Biochemistry
DOI: 10.1021/bi4003327


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