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The three-dimensional structural surface of two beta-sheet scorpion toxins mimics that of an alpha helical dihydropyridine receptor segment

Green, Daniel; Pace, Suzy M; Curtis, Suzanne; Sakowska, Magdalena; Lamb, Graham; Dulhunty, Angela; Casarotto, Marco


An α-helical II-III loop segment of the dihydropyridine receptor activates the ryanodine receptor calcium-release channel. We describe a novel manipulation in which this agonist's activity is increased by modifying its surface structure to resemble that

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: Biochemical Journal
DOI: 10.1042/BJ20021488


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