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Anthracene-polyamine conjugates inhibit in vitro proliferation of intraerythrocytic plasmodium falciparum parasites

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Niemand, J; Burger, Pieter; Verlinden, Bianca K; Reader, Janette; Joubert, Annie M; Kaiser, Annette; Louw, A I; Kirk, Kiaran; Phanstiel IV, Otto; Birkholtz, L

Description

Anthracene-polyamine conjugates inhibit the in vitro proliferation of the intraerythrocytic human malaria parasite Plasmodium falciparum, with 50% inhibitory concentrations (IC50s) in the nM to ±Mrange. The compounds are taken up into the intraerythrocyt

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
URI: http://hdl.handle.net/1885/72743
Source: Antimicrobial Agents and Chemotherapy
DOI: 10.1128/AAC.00106-13
Access Rights: Open Access

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