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EGFR gene methylation is not involved in Royalactin controlled phenotypic polymorphism in honey bees

Kucharski, Robert; Foret, Sylvain; Maleszka, Ryszard


The 2011 highly publicised Nature paper by Kamakura on honeybee phenotypic dimorphism, (also using Drosophila as an experimental surrogate), claims that a single protein in royal jelly, Royalactin, essentially acts as a master "on-off" switch in development via the epidermal growth factor receptor (AmEGFR), to seal the fate of queen or worker. One mechanism proposed in that study as important for the action of Royalactin is differential amegfr methylation in alternate organismal outcomes....[Show more]

CollectionsANU Research Publications
Date published: 2015
Type: Journal article
Source: Scientific Reports
DOI: 10.1038/srep14070
Access Rights: Open Access


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