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Polymorphism in endothelial connexin40 enhances sensitivity to intraluminal pressure and increases arterial stiffness

Chaston, Daniel; Baillie, Brett; Grayson, Thomas; Courjaret, Raphael J; Heisler, Jillian M; Lau, Katherine A; Machaca, Khaled; Nicholson, Bruce; Ashton, Anthony; Matthaei, Klaus; Hill, Caryl


OBJECTIVE - : To determine whether impairment of endothelial connexin40 (Cx40), an effect that can occur in hypertension and aging, contributes to the arterial dysfunction and stiffening in these conditions. APPROACH AND RESULTS - : A new transgenic mouse

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
Source: Arteriosclerosis Thrombosis and Vascular Biology
DOI: 10.1161/ATVBAHA.112.300957


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