The biological role of Asn-linked glycosylations of DENV-2 E protein
The envelope proteins of many viruses are glycosylated, where the glycans on the virion surface have been shown to be important, in addition to their strictly structural role, in various aspects of the virus life cycle, such as receptor-binding and escape from antibody recognition. Dengue virus (DENV) is in terms of human disease frequency the most important member of the flaviviruses, a group of small, enveloped, plus-strand RNA viruses. The four DENV serotypes differ from all other...[Show more]
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