Models of Permeation in Ion Channels
Ion channels are formed by specific proteins embedded in the cell membrane and provide pathways for fast and controlled flow of selected ions down their electrochemical gradient. This activity generates action potentials in nerves, muscles and other excitable cells, and forms the basis of all movement, sensation and thought processes in living beings. While the functional properties of ion channels are well known from physiological studies, lack of structural knowledge has hindered development...[Show more]
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