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Revisiting the hygiene hypothesis in gastrointestinal allergy

Chin, James


The "hygiene hypothesis" in its original form hypothesized that infection in early childhood acquired through unhygienic contact with siblings or the mother may prevent the development of allergic disease. Several recent epidemiologic surveys showing an inverse relationship between the frequency of infectious disease and the incidence of allergic diseases lend support to this hypothesis. Allergen sensitization of the immune system can occur early in utero against a background of neonatal...[Show more]

CollectionsANU Research Publications
Date published: 2002
Type: Journal article
Source: Current Opinion in Gastroenterology
DOI: 10.1097/00001574-200211000-00012


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