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Connexin37 is major connexin expressed in media of caudal artery

Rummery, Nicole; Hickey, Haruyo; McGurk, Gordon B; Hill, Caryl

Description

Objective - To determine the connexins (Cxs) involved in intercellular coupling within vascular muscle, the present study has quantified mRNA and protein expression for Cx37, Cx40, Cx43, and Cx45 in the caudal artery (CA) and thoracic aorta (ThA) of the rat. Methods and Results - Real-time polymerase chain reaction and immunohistochemistry identified Cx37 as the most abundantly expressed Cx in the CA, with fine punctate staining observed in the media. Conversely, mRNA for Cx43 was 40-fold...[Show more]

CollectionsANU Research Publications
Date published: 2002
Type: Journal article
URI: http://hdl.handle.net/1885/71337
Source: Arteriosclerosis Thrombosis and Vascular Biology
DOI: 10.1161/01.ATV.0000028814.45706.E5

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