Channels underlying neuronal calcium-activated potassium currents
In many cell types rises in cytosolic calcium, either due to influx from the extracellular space, or by release from an intracellular store activates calcium dependent potassium currents on the plasmalemma. In neurons, these currents are largely activated following calcium influx via voltage gated calcium channels active during the action potentials. Three types of these currents are known: Ic, IAHP and IsAHP. These currents can be distinguished by clear differences in their pharmacology and...[Show more]
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|Source:||Progress in Neurobiology|
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