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Molecular evolution of VH9 germline genes isolated from DBA, BALB, 129 and C57BL mouse strains and sublines

Zylstra, Paula; Franklin, Andrew; Hassan, Karl; Powell, Kim; Steele, Edward J; Blanden, Robert


We have used the polymerase chain reaction (PCR) in an attempt to clone and sequence the exons and hitherto unavailable contiguous flanks of all members of the small VH9 germline gene family from inbred mouse strains and sublines that have had a common ancestry within the last century, and to analyze the molecular evolution of these sequences. Fifteen genuine germline genes were isolated (designated VH9.1 through VH9.15) from strains and sublines of DBA, BALB, 129 and C57BL inbred mice. Of the...[Show more]

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: Immunogenetics
DOI: 10.1007/s00251-003-0565-x


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