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Skeletal muscle excitation-contraction coupling: Who are the dancing partners?

Rebbeck, Robyn; Karunasekara, Yamuna; Board, Philip; Beard, Nicole; Casarotto, Marco; Dulhunty, Angela


There is an overwhelming body of work supporting the idea that excitation-contraction coupling in skeletal muscle depends on a physical interaction between the skeletal muscle isoform of the dihydropyridine receptor L-type Ca2+ channel and the skeletal isoform of the ryanodine receptor Ca2+ release channel. A general assumption is that this physical interaction is between "critical" residues that have been identified in the II-III loop of the dihydropyridine receptor alpha subunit and the...[Show more]

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
Source: The International Journal of Biochemistry and Cell Biology
DOI: 10.1016/j.biocel.2013.12.001


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