Skeletal muscle excitation-contraction coupling: Who are the dancing partners?
There is an overwhelming body of work supporting the idea that excitation-contraction coupling in skeletal muscle depends on a physical interaction between the skeletal muscle isoform of the dihydropyridine receptor L-type Ca2+ channel and the skeletal isoform of the ryanodine receptor Ca2+ release channel. A general assumption is that this physical interaction is between "critical" residues that have been identified in the II-III loop of the dihydropyridine receptor alpha subunit and the...[Show more]
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|Source:||The International Journal of Biochemistry and Cell Biology|
|01_Rebbeck_Skeletal_muscle_2014.pdf||2.12 MB||Adobe PDF||Request a copy|
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