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How does overcoordination create ion selectivity?

Thomas, Michael; Jayatilaka, Dylan; Corry, Ben


Some biological molecules can distinguish between ions of similar nature, which may be achieved by enforcing specific coordination numbers on ions in the binding site. It is suggested that when this number is favourable for one ion type, but too large for another, this creates ion selectivity through the proposed mechanism of 'overcoordination'. Much debate has occurred about the role overcoordination plays, and suggestions made as to how molecules can enforce particular coordination numbers,...[Show more]

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
Source: Biophysical Chemistry
DOI: 10.1016/j.bpc.2012.11.005


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